About Us

Company Mission

 

JOINN Biologics is a Bay Area, California-based CMO company that is committed to the advancement of biopharmaceutics through its premier contract development and manufacturing services for biologics and advanced therapies. JOINN Biologics aims to provide a complete range of services from early custom development to clinical manufacturing for our global clients. We will work closely with our partners and clients to further accelerate the development of high-quality biologics to meet patient’s needs and deliver long-lasting value to biopharmaceutical industry.

 

Management Team

Dr. Tao He, Co-Founder, SVP

20+ years in pharma (Novartis, Wyeth, and Pfizer). Led multiple biologics programs from preclinical through IND filing

Dr. Baolu Chen, SVP

20+ years in pharma (Amgen, Chiron, Sangamo, Shanghai Henlius Biotech). Expert in quality systems, CMC & project management, and IND filing and BLA registration

Jonathan Blackie, VP

25+ years leadership roles (Bayer, Biomarin) in Manufacturing Sciences, Commercial and Clinical Manufacturing Operations and Global Business Process Integration.

Dr. Wenrong Jiang, Sr. Director

20 years in pharma (Roche, Pfizer) for drug R&D, expert in antibody drug & cell line development

Dr. Shumin Yang, Sr. Director

15+ years in biologic product and process development, especially Upstream Process Development (Boehringer Ingelheim, Catalent)

JOINN GROUP

JOINN Biologics

Pre-Clinical and Clinical Manufacturing

Pre-clinical Evaluation

JOINN Laboratories is the sister company of JOINN Biologics, and has an excellent track record spanning over two decades for non-clinical safety evaluation.


Announcement

JOINN Biologics Inc. receives US $60 Million Series A financing led by HG Capital, the fund is dedicated to help JOINN Biologics build a comprehensive biopharmaceutical service platform and become a global biologics CDMO leader.

JOINN Biologics Inc. (hereinafter referred to as “JOINN Bio”) recently completed a $60 million Series A financing. The financing was led by HG Capital, and Nestbio Capital, Hong Kong LINKAGE Holdings, Xiangtang Capital and other institutions jointly participated in the investment. This round of financing will be mainly used for the construction of 100,000-liter capacity for biopharmaceutical manufacturing of JOINN Bio, as well as business expansion in China and the United States.

Experienced and dedicated technical team

Established in early 2018, JOINN Bio has a core technical team of nearly 200 staff from both China and the United States. 20% of JOINN Bio’s experts have more than 15 years’ experience in the field of protein-based drug R & D and production. JOINN Bio provides its global customers with one-stop solutions from cell line construction, developability analysis, process development, and product quality research to pilot plant and commercial production. JOINN Bio is well equipped to meet the diverse needs of its customers.

Tao He, Ph.D., Co-Founder

Dr. He has more than 20 years of experience in the discovery and development of innovative protein and monoclonal antibodies therapy. He has working experience in world renowned pharmaceutical companies, such as Novartis, Wyeth and Pfizer. Dr. He is a subject matter expert and industry leader in developability analysis and protein drug characterization for biologics development. As a team leader, he has led and directly participated in the development of multiple biomacromolecules that have been successfully approved for clinical and commercial development.

Shusheng Geng, Ph.D., Co-Founder

Dr. Geng has more than 20 years’ experience in research and development, and management in biological macromolecular medicines. He has managed and directly participated in the development of nearly 20 antibody drugs. These drugs have gradually entered different stages of clinical trials, targeting indications such as Oncology, Infectious diseases, and Immunotherapy. Dr. Geng has extensive experience in cell line construction, process optimization and scale-up.

Bao-Lu Chen, Ph.D., Senior Vice President

Dr. Chen has nearly to 30 years’ experience in the field of protein drugs, monoclonal antibodies, and gene therapies. He has worked for internationally renowned companies such as Amgen, Chiron, Henlius. Dr. Chen has extensive experience in CMC operation management, drug production, quality management, and domestic and international registration.


Leverage JOINN brand advantages to provide one-stop service for the biopharmaceutical industry

By leveraging JOINN Labs brand and customer resources, JOINN Bio provides comprehensive services covering antibody drugs, recombinant protein drugs, gene therapy, and cell therapy; JOINN Bio offers an end-to-end, concept to commercial manufacturing one-stop service for protein drug development to the biopharmaceutical industry.

International services to achieve dual registration in China and the US

As a domestic CDMO service provider with a CGMP production site in the United States, JOINN Bio’s US manufacturing facility is equipped with bioreactors’ production capacity of 1000 L and 2 × 500 L.  JOINN Bio US plant has accumulated vast experience in protein drugs large-scale production, operation, and management. At the same time in China, JOINN Bio has built production facility to meet the 2 × 200 L, 2 × 500 L manufacturing scale and supporting Process Development activities. JOINN Bio plans to build a production facility with 100,000-liter manufacturing capability for BDS (bulk drug substance) in China that meets the GMP standards of China, the United States, and the European Union. The production facilities and experienced teams in the United States and China and will support biopharmaceutical companies to achieve dual registration in these two countries and strategically plan multi-region manufacturing.


Provide cell lines with intellectual property to alleviate industry bottlenecks

Facing the increasingly strict environment for the regulatory approval of new drugs, intellectual property issues are essential to the success of research and development of new therapies by biopharmaceutical companies. Since its inception, JOINN Bio has developed an engineered cell line with full intellectual property rights. This helps to reduce the large amount of intellectual property expenses in the late commercialization of novel therapies. Currently, JOINN Bio has established a host cell system that satisfies the requirement from pilot to commercial production. In addition, JOINN Bio has established quality standard, release assays, and in-depth structural characterization for monoclonal antibodies and recombinant protein drugs.


Join hands with professional investors to build a leading company in the pharmaceutical CDMO field

Regarding the investment in JOINN Bio, Zeng Zhiqiang, a managing partner at HG Capital Medical Fund, said, “HG Medical has always adhered to the investment strategy of working with the industry leader in a specific segment, and is definitely optimistic about opportunities in the CRO and CDMO field driven by the global, especially China or other emerging-market countries, upsurge of innovative medicine. JOINN Labs is an industry leader in the field of biomedical CRO through years of hard work. In addition to strong technology platform and high-quality service system, more than 60% of Chinese biopharmaceutical companies are JOINN Labs’ customer. The excellent track record and brand recognition form the foundation to extend to those customers in the area of CDMO services.

We look forward to the joint effort of HG Medical Fund and JOINN to leverage HG Medical’s resources in the field of biomedicine and clinical services to assist JOINN Bio quickly becoming a world-class biopharmaceutical CDMO. “

Ziqiang Zeng
Ziqiang Zeng, Managing partner at Huagai Capital Medical Fund
About JOINN Bio

Established in early 2018, JOINN Bio is a share-holding subsidiary of JOINN Labs Co., Ltd., and is committed to becoming the world’s leading and the most trusted biopharmaceutical CDMO. JOINN Bio has a core technical team rich with industry experience, familiarity with US, EU and Chinese new drug regulations, and a host cell line with full intellectual property rights. With manufacturing facilities in both the United States and China, JOINN Bio provides one-stop solutions from cell line development, developability analysis, process development and scale up optimization, product quality research, pilot plant and commercial manufacturing to global innovative drug research and development institutions.

About HG Capital

HG Capital is a private equity investment institution co-founded by a group of professionals from well-known investment institutions at home and abroad. The company’s vision is to become a local asset management institution with international influence, focusing on private equity investment in the Chinese market, promoting the growth of Chinese SMEs into industry leaders. At present, it manages a number of equity investment funds such as medical health funds, TMT funds, cultural funds, and the management asset exceeds USD 2.2 billion.

NEWS

JOINN Biologics gave an oral presentation regarding Case Study of Antibody Developability Assessment at BioProcess International Conference (Gene to Market Track) on September 10, 2019, at Boston Convention and Exhibition Center (BCEC).
JOINN Biologics was invited to a panel discussion of “Innovative and Collaborative Contract Services to Accelerate Drug Development” at CABS 2019 BioPacific Conference, June 22, 2019, San Mateo, CA
JOINN Biologics presented a poster regarding cell line development at the Cell Line Development and Engineering Conference, June 18-20, 2019, San Francisco, CA
JOINN Biologics presented a poster regarding developability assessment at PEGS the Essential Protein Engineering Summit, April 8-12, 2019, Boston, MA

Careers

Life at JOINN Biologics

JOINN Biologics is a young company filled with energy. Life here is exciting. Here you can fully utilize your own expertise and you can be cross-trained by different departments, for skills from development to manufacturing, and to quality. No matter what field you were in, you can still learn new skills here.

Benefits

JOINN Biologics is an equal opportunity employer offering competitive compensation and benefits, which includes:

  • Health insurance
  • Dental insurance
  • Vision insurance
  • Retirement plan
  • Paid time off
  • Parental leave
 

We are looking for highly motivated and determined individuals to fill the positions below.

To apply, please send your CV and cover letter to career@joinnbio.com

Principal Scientist, Biologics Formulation

Essential Duties and Responsbilities:
The Formulation Principal Scientist will provide technical leadership for the development of pre-clinical and early clinical stage candidates forms following quality by design (QbD) principles for the delivery protein-based therapeutic agents. The successful candidate will be expected to drive programs from inception through pre-clinical manufacture/screening, technology transfer, early cGMP manufacture, working closely with Quality and CMC counterparts as well as any necessary analytical method development, specification development, and assessment of stability data/programs.
 
  • Independently performs and implements formulation strategies
  • Development of inject-able biologics dosage forms following quality by design (QbD) principles
  • Identifies drug product critical quality attributes impacting safety, efficacy, and manufacturing robustness. Provides input to define phase appropriate regulatory specifications
  • Performs screening of buffers, excipients, solubilizers, etc.
  • Preformulation characterization of preclinical and clinical compounds
  • Authoring and review of written documents including development reports, technical memos, etc.
  • Serves as formulation lead in multidisciplinary project teams and/or sub-teams
  • Work effectively in a cross-functional matrix environment, with internal and external customers and proactively communicate with internal and external stakeholders.
Required Experience / Qualifications
  • 10+ years’ industry experience with BS degree in related scientific discipline, or 8+ years’ industry experience with MS degree in related scientific discipline.
  • Will have expert understanding of preformulation and formulation area and uses published literature to extend understanding as well as consulting internal and external experts as needed
  • Highly independent and self-motivated and integrates well within a team
  • Ability to establish and maintain effective working relationships
  • Strong ability to trouble-shoot technical problems
  • Detail oriented, with good organizational skills and project management skills
  • Able to work in a high paced team environment meet deadlines and prioritize work on multiple projects
  • Excellent oral and written communication skills

Job Type: Full-time

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

Head of Purification, Process Development

We are seeking the Head of Purification, Process Development. The incumbent will work with internal and external partners, to develop purification strategies to support production of monoclonal antibodies and recombinant proteins. The candidate should possess extensive knowledge and experience in separation sciences, and basic understanding of GLP and GMP regulations applicable to the biologics product and process development. The individual will be responsible for smooth tech transfer within the organization and with our clients.

Essential Duties and Responsbilities:
  • Lead and manage a team of scientists/engineers focused on downstream purification process development activities. Provide leadership to resolve purification investigations and technical issues in the process development and manufacturing areas.
  • Establish and maintain familiarity with contemporary industrial practices and technology focused on purification process development. Manage day-to-day laboratory operations, including prioritizing samples and studies, scheduling analyst assignments, and tracking timely progress of critical samples and studies to support project timelines. Provide reports on department output that evaluate operating effectiveness.
  • Provide strategic leadership in resource allocation and prioritization of analyses to assure alignment of department objectives and timely execution of experiments to support clinical development programs.
  • Motivated to drive operational excellence, including support for efficiency/productivity initiatives, and GxP/safety compliance.
Experience / Skills
  • Doctorate (Ph.D.) degree in chemical engineering, bioengineering, biochemistry, biotechnology, biology, , or a related field, with at least 2 years of industrial experience is preferred. B.S./M.S. with at least 5 years of industrial experience are also considered.
  • Demonstrated ability to lead teams, including cross-functional initiatives & strong ability to foster a collaborative work environment.
  • In-depth understanding of methodology and data interpretation in separations sciences and processes.
  • Expert in purification technologies from lab to manufacturing scale, in operating chromatography equipment such as Akta or filtration equipment, and in application of statistical/DOE tools for process development and data analysis.
  • Excellent communication and people management skills.
  • Ability to execute studies and experiments in the context of supporting long-term commercialization plans

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.

Accountant

As a key member of our Accounting team, this role provides support to Accounting and Finance staff, as well as our internal functional customers and external vendors, and ensures complete, timely, and accurate Accounting and Accounts Payable functions within the department. Solid accounting knowledge is required.

Essential Duties and Responsbilities:
  • Account for current month’s activities and post the journals in quick book/Sage X3 ERP system.
    • Perform monthly, quarterly and annual accounting activities including recording all activities, invoices, reconciliations of bank and credit card accounts, coordination and completion of annual audits, and reviewing financial reports/support as necessary.
    • Analyze and report on financial status including income statement variances, communicating financial results to management, budget preparation and analysis.
    • Improve systems and procedures and initiate corrective actions.
  • Manage cash and payment request and perform the duty of Accounts Payable function.
    • Process invoices for payment, reviews for accuracy and authenticity,communicate with vendors on payment information and reconcile the difference. Maintains accounts payable files and records including filing as needed.
    • Audit employee expense reports, verify supporting document and process payments.
  • Assist in development and maintenance of accurate standard costing for all projects.
  • Perform annual physical count of inventory and fixed assets.
  • Ensure compliance with applicable standards(i.e. GAAP, FASB), rules, regulations, and systems of internal control.
  • Aid in the implementation of new accounting policies, standards, and guidelines.
  • Perform other duties as assigned.
Required Qualifications:
  • BA or advanced degree in Accounting, with 3+ years’ experience in Accounting.
  • 1+ years’ Accounts Payable experience.
  • Knowledge and understanding of GAAP.
  • Proficient in Microsoft Office (incl. Excel, Outlook, PowerPoint, Teams, and Word).
  • Accounting software experience, Quick Books required. Sage ERP experience preferred.
  • Ability to deliver accurate, timely financial results.
  • Proven communication and interpersonal skills.
  • Customer Service Orientation to internal functional teams and external vendors.
  • Ability to work a collaborative, fast-paced environment.
  • Understands confidentiality
  • Results Driven.
  • Detail Orientation.
Preferred Qualifications:
  • Knowledge of ERP processes and controls.
  • Knowledge of Project Accounting.
  • Bilingual in Mandarin and English.

Location: Richmond, CA 94806 

Work authorization: United States (Required) 

To apply, send your CV to career@joinnbio.com.